Saturday, December 31, 2011

Huntsman on Iowa absence: 'They pick corn in Iowa' (AP)

WASHINGTON ? Former U.S. Ambassador Jon Huntsman is defending his refusal to compete in the leadoff Iowa Republican precinct caucuses, focusing instead on New Hampshire.

Huntsman tells CBS's "The Early Show" the formula, so far as he is concerned, is quite elementary. Says Huntsman: "They pick corn in Iowa. They pick presidents in New Hampshire."

The former Utah governor has made little effort to win in Iowa, focusing mostly on New Hampshire in the early going. He has remained in the lower tier of candidates as others, including Newt Gingrich and Rick Santorum ? and at one time, Herman Cain ? soared in the polls. He was ambassador to China for President Barack Obama, but says that shouldn't be used against him as he seeks the Republican presidential nomination.

Source: http://us.rd.yahoo.com/dailynews/rss/gop/*http%3A//news.yahoo.com/s/ap/20111229/ap_on_el_ge/us_huntsman_republicans_iowa

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Here?s Your Car Back (Theagitator)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/180728235?client_source=feed&format=rss

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China: Confession in $10 billion smuggling case

China's most-wanted man, who was deported from Canada in July after a decade-long legal battle, has admitted to his crimes and will now be handed over to prosecutors, state media reported Friday.

Beijing had sought the deportation of Lai Changxing for years, accusing him of running a multi-billion dollar smuggling ring in the southeastern city of Xiamen in the 1990s.

The move brings authorities a step closer to a conclusion in one of China's most lurid, long-running corruption cases.

Prosecutors indicted Lai for allegedly masterminding a network that smuggled everything from cigarettes to cars and oil and bribed dozens of government workers between 1996 and 1999, China's state broadcaster CCTV reported.

Lai and other key members of the syndicate have "confessed to the facts of the smuggling and bribery charges without concealing anything," the report said.

The "legal rights" of Lai and the other suspects were "fully guaranteed," with Lai able to meet with his lawyer, state radio added.

Lai became China's most-wanted man after he fled to Canada in 1999 and fought extradition for 12 years.

Nothing had been heard of him since he was returned to China over the summer.

Liquor and prostitutes
Before fleeing to Canada, he lived a life of luxury in China complete with a bulletproof Mercedes Benz. He is alleged to have run a mansion in which he plied officials with liquor and prostitutes.

At the time, state TV splashed pictures of the network's allegedly ill-gotten gains: A tiger skin rug laid out on a conference table, confiscated cars belonging to corrupt bureaucrats, a sack of gold rings, and a picture of a young woman, said to be a lover kept for one official by Lai.

Chinese media have said Lai's alleged smuggling operation was valued at $10 billion.

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China put more than 300 suspects on trial and sentenced 14 to death, including provincial officials and a former vice minister of public security, in a case Beijing has used for a propaganda campaign against corruption.

China's Communist Party has struggled to control widespread practices of embezzlement, taking kickbacks, and influence peddling that have degraded public faith and sometimes led to violent protest.

In Canada, Lai had avoided deportation by arguing he could face the death penalty or be tortured and would not get a fair trial in his home country.

But that legal battle ended in July when a federal court in Vancouver ruled Lai should not be considered a refugee and upheld his deportation.

China promised Canada that Lai would not get the death penalty in 2001 when then-President Jiang Zemin sent the Canadian prime minister at the time, Jean Chretien, a diplomatic note with assurances Lai would not be executed if returned.

Loopholes exploited
Lai's alleged crimes occurred in the special economic zone of Xiamen in Fujian province in the mid-1990s when Jia Qinglin, now the ruling Communist Party's fourth most senior leader, was the province's party boss.

Beijing has accused Lai's business empire, the Yuanhua Group, of bribing officials to allow a massive smuggling ring. Jia's wife, Lin Youfang, was among those implicated in the scandal. She denied any wrongdoing.

Lai admitted in a 2009 interview with Toronto's Globe and Mail newspaper that he had avoided taxes by exploiting loopholes in the law, but he denies bribery charges.

Lai may face life imprisonment, state media has reported. But some legal experts and human rights activists have said it was unlikely Lai could receive a fair trial in China.

The Associated Press and Reuters contributed to this report.

Source: http://www.msnbc.msn.com/id/45825335/ns/world_news-asia_pacific/

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Weaker Demand for Italian Debt Drives Euro Down

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Source: webdev.credittrends.moodys.com --- Thursday, December 29, 2011
Investors remained cautious after Italian 10-year bond yields stayed above the 7% level ...

Source: http://credittrends.moodys.com/pro/article.asp?cid=227317

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Friday, December 30, 2011

Adele Notches Best Sales Year Since Usher's Confessions

In 2011, 21 moved more than 5.6 million copies in the U.S.
By Gil Kaufman


Adele
Photo: Getty Images

The music industry has been stuck in a rut for nearly a decade. But every once in a while, it still manages to produce one of those unstoppable hit albums that give everyone that good old feeling.

This year's model is Adele's 21, which not only sold more copies than any other album in the U.S. in 2011 (more than 5.6 million to date), but which has also moved the most units of any artist since 2004. According to a Reuters report, those gaudy figures (which top 15 million worldwide) make the British songbird the first artist to cross the 5 million mark in one year since Usher did it with his fourth studio album, Confessions, which sold 7.9 million units more than seven years ago.

And to think she did it by releasing just two mega singles, "Rolling in the Deep" and "Someone Like You," and barely touring North America due to recurring vocal issues.

There have been other big hits along the way to Adele's mark, including Eminem selling more than 3.4 million copies of his comeback Recovery album last year and Taylor Swift taking the honors in 2009 with Fearless, which sold 3.2 million copies. But none have come as close to Usher's mark in the interim.

There doesn't seem to be any chance Adele will be surpassed by the end of the year: The closest contenders are Lady Gaga's Born This Way (2.08 million) and Michael Bublé's Christmas (2.4 million). The other good news is that overall music sales are expected to be up slightly (3 percent) by the end of this year, marking the first time that's happened since 2004.

Related Artists

Source: http://www.mtv.com/news/articles/1676522/adele-usher-best-sales-record.jhtml

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A Tale Of Modern Thieves (Roleplayers needed!)

Hello, there, everyone! I'd just like to let you all know (despite the fact that it's in the "New Roleplays" bar at the moment) that I've just created a roleplay called "A Tale Of Modern Thieves," as you can probably gather from the title of this thread. I just thought I'd drop a link so we can get players faster and start sooner. If you have a question, feel free to PM me. :D

Click here.

Or follow this link. http://www.roleplaygateway.com/roleplay/a-tale-of-modern-thieves/

"Those who make peaceful protest impossible will make violent protest inevitable."

John F. Kennedy, 35th President of the United States of America

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Riot at the Mall of America (Powerlineblog)

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Thursday, December 29, 2011

GSM phones vulnerable to hijack scams: researcher (Reuters)

BERLIN (Reuters) ? Flaws in a widely used wireless technology could allow hackers to gain remote control of phones and instruct them to send text messages or make calls, according to an expert on mobile phone security.

They could use the vulnerability in the GSM technology -- which is used by most telecom operators globally and by billions of people -- to make calls or send texts to expensive, premium phone and messaging services in scams, said Karsten Nohl, head of Berlin-based Security Research Labs.

Nohl is a well-regarded expert on mobile security who last year identified a bug in GSM technology that makes calls vulnerable to tapping. He says he is calling attention to these flaws to pressure the industry into beefing up the security of their products.

Mobile security is a hot issue because hackers are paying unprecedented attention to the devices as smartphone sales have outpaced sales of PCs.

Only a few flaws have been found in GSM technology - which stands for Global System for Mobile Communications - over its 20-year history. Industry lobby group GSMA said on Tuesday it did not expect the new findings to affect its views on the security of the technology.

"The GSMA and its mobile network operator members are confident in the security of existing 2G GSM networks and real attacks on real networks against real customers are most unlikely," it said in a statement, adding that newer technologies are safer and not impacted by the new research.

GSMA's statement "on anticipated GSM security announcements" did not make clear whether the industry group had actually seen Nohl's latest research.

Security experts have previously identified a small number of viruses designed to infect smartphones, allowing hackers to take control of the devices and force them to make calls or send text messages. But Nohl said he has discovered a way to leverage previously disclosed vulnerabilities in GSM technology that could potentially threaten hundreds of thousands of phones.

"We can do it to hundreds of thousands of phones in a short time frame," Nohl told Reuters ahead of a presentation on the topic at a hacking convention in Berlin on Tuesday.

SECTOR IN FOCUS

Smartphone malware is popping up at an unprecedented rate as people put more and more valuable information on the devices, using them to hold corporate secrets, conduct banking and function as digital wallets.

GSM became the dominant mobile technology globally in the late 1990s and even though new, faster mobile networks have been rolled out across the world, operators have stuck to their GSM networks to support older phones and to offer service when new networks fail.

The Berlin convention takes place just days after U.S. security think tank Strategic Forecasting Inc (Stratfor) said its website had been hacked and that some names of corporate subscribers had been made public. Activist hacker group Anonymous claimed responsibility.

Attacks on corporate landline phone systems are fairly common, often involving bogus premium-service phone lines that hackers set up in countries in Eastern Europe, Africa and Asia.

Fraudsters make calls to the numbers from hacked business phone systems or mobile phones, then collect their cash and move on before the activity is identified.

The phone users typically do not realize the problem until after they receive their bills, and telecommunications carriers often end up footing at least some of the costs.

Even though Nohl will not present all details of possible attacks at the conference, he said hackers will usually replicate the code needed for attacks within a few weeks.

T-MOBILE, SFR LEAD NEW RANKING

Mobile networks of Germany's T-Mobile and France's SFR offer their clients the best protection against online criminals wanting to intercept their calls or track their movements, according to a new ranking Nohl will unveil at his presentation.

The new ranking, at gsmmap.org, is conducted by security researchers, who hope this will heighten the awareness of operators and consumers on the vulnerability of their mobile communications.

Researchers reviewed 32 operators in 11 countries and rated their performance based on how easy it was for them to intercept the calls, impersonate someone's device or track the device.

"None of the networks protects users very well," Nohl said.

The sample is set to grow from 32 carriers dramatically next year as the tool enables anyone to participate in data gathering

by downloading measuring software to their phones.

Nohl said mobile telecom operators could easily improve their clients' security, in many cases by just updating their software.

Researchers reviewed operators in Austria, Belgium, the Czech Republic, France, Germany, Hungary, Italy, Morocco, Slovakia, Switzerland and Thailand.

(Additional reporting by Jim Finkle; Editing by Matt Driskill, Vinu Pilakkott and Matthew Lewis)

Source: http://us.rd.yahoo.com/dailynews/rss/security/*http%3A//news.yahoo.com/s/nm/20111228/tc_nm/us_mobile_security

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Wednesday, December 28, 2011

Maccabee/Syrian 'Angry Birds'? You bet, at York's Jewish Community Center

It was "Angry Birds" meets ancient Jewish history.

The battle between the Maccabee soldiers and the Syrian army that took place more than 2,000 years ago was re-enacted Sunday at York's Jewish Community Center -- in the style of the popular "Angry Birds" video game.

True to history, the Maccabees won, helping to preserve religious freedom.

Kids shot kickballs out of a life-size slingshot toward blow-up pigs and boxes -- the kickballs were marked with Jewish symbols, and the pigs represented the Syrian army.

Nine-year-old Leon Bellenbaum, of Springettsbury Township, said his family attends the Celebrate Chanukah event every year, but this year he was looking forward to the

From the left, Emma Ehrlich, age 4, is held in suspense as Emme Applefeld, age 8, is assisted by Lyn Mendlowitz with the Giant Maccabee Angry Bird shooter before she tries to hit the wall of boxes. (YORK DAILY RECORD/SUNDAY NEWS - PAUL KUEHNEL)

"Angry Birds" battle the most.

Leon and his brother Simon, 5, raved about the latke-eating contest, too.

The event began with a social period and a menorah lighting, then broke off into other activities such as a dreidel hunt, Hanukkah "Jeopardy" and face-painting for all ages before the final battle.

Laura Merklin -- the youth, teen and family coordinator for the JCC -- said the event strives to provide Jewish children with meaningful experiences and educate the community about the Hanukkah season.

Merklin, of York Township, said she came up with the "Angry Birds" simulation from a YouTube video and decided it was a good way for kids and community members to visualize the complexities of the war between the Maccabees and the Syrians.

"We really wanted to do something fun and something that would get the kids going," Merklin said.

JCC Programming Director Bill Walter, of New Jersey, said the education hidden among the games and fun activities of the day was the most important part of the celebration.

"(The events) bring back old traditions of Hanukkah," Walter said.

DAILY RECORD/SUNDAY NEWS -- PAUL KUEHNEL

Emma Erhlich, 4, left, is tense with suspense as Emme Applefeld, 8, center, is helped by Lyn Mendlowitz with the 'Angry Bird' slingshot during a fun re-enactment of a more-than-2,000-year-old battle at Sunday's Celebrate Chanukah event at York's Jewish Community Center. Kids portraying Maccabbees shot kickballs at blow-up pigs and boxes -- representing the Syrian army -- in an educational game that helped teach children and community members the history of Hanukkah.


DAILY RECORD/SUNDAY NEWS -- PAUL KUEHNEL

Steven Astrachan, 13, builds up the Syrian army's wall of boxes again Sunday during an 'Angry Birds'-esque re-enactment of a historic battle against the Maccabbees.

Source: http://www.inyork.com/ci_19575090?source=rss_viewed

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Caution mutes US response to N. Korea

The Obama administration's cautious response to the death of North Korean dictator Kim Jong Il reflects unease and uncertainty about the leadership transition in the reclusive country that has confounded U.S. presidents for 60 years.

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North Korea, the "hermit kingdom," has vexed the United States and its allies with war, nuclear tests, missile launches, belligerence and bellicose bombast. But since he took office in 2009, President Barack Obama has had to deal with North Korea at perhaps its most secretive point: an unclear succession amid a time of deep concern about the stability of the regime.

Thus, the administration's carefully worded public messages have underscored its desire for better relations with the autocratic nation and its concern about the welfare of the North Korean people. They are also gentle reminders that Washington expects Pyongyang to follow through on denuclearization pledges and improve ties with its neighbors, particularly South Korea.

The kid-gloves treatment accorded to the North's youthful new leader, Kim's twenty-something son Kim Jong Un, has attracted criticism from some who see this is a moment to make a forceful case for dramatic reform and regime change.

But without solid intelligence on the opaque transition process and fearful of misunderstandings that could lead to provocations with the notoriously erratic North, U.S. officials have concluded the best course is to say little, wait and watch.

Indeed, the administration's initial reactions to Kim's death have contained little substance at all.

"All I can say is that we're monitoring the situation closely," White House press secretary Jay Carney said Wednesday as North Korean state media broadcast pictures of wailing mourners, apparently overcome with grief. "Kim Jong Il had designated Kim Jong Un as his official successor, and at this time we have no indication that that has changed."

Carney added: "We hope that the new North Korean leadership will take the steps necessary to support peace, prosperity and a better future for the North Korean people, including through acting on its commitments to denuclearization."

Those comments echoed words from Secretary of State Hillary Rodham Clinton. On Monday, more than 16 hours after Kim's death was announced, she was the first senior U.S. official to comment publicly, calling for "a peaceful and stable transition in North Korea" and expressing hope that it would not affect "regional peace and stability."

Ironically, it was Clinton who first stirred the pot about a possible succession crisis in North Korea.

Nearly three years ago, on her first trip to Asia as secretary of state, she stunned diplomatic circles with a frank appraisal of U.S. concerns amid speculation about the health of Kim Jong Il, who had suffered a stroke in 2008, and his choice of a successor.

"If there is a succession, even if it's a peaceful succession, that creates more uncertainty and it also may encourage behaviors that are even more provocative as a way to consolidate power within the society," Clinton told reporters on Feb. 20, 2009.

Her remarks on a previously taboo subject sparked great debate. In Seoul the next day, she expressed surprise at the uproar, noting that reports of Kim choosing his youngest son Kim Jung Un to succeed him had "been in the news for months."

"I don't think that it's a forbidden subject to talk about succession in the hermit kingdom," Clinton said. "In fact, it seems to me it's got to be factored into any policy review that one is undertaking."

That same month, U.S. diplomats were scrambling to collect any information they could about Kim Jong Un from South Korean, Chinese and Japanese officials and experts, according to leaked State Department cables published by WikiLeaks.

Unfortunately for the Americans, their interlocutors had sharply divided opinions, according to the cables. Some predicted the North Korean regime would collapse politically within two to three years of Kim Jong Il's death. Others foresaw a power struggle between the young and untested Kim Jong Un and rivals in the elite, but differed over who would prevail. Others believed there would be little change.

One apparent area of convergence, however, was that most South Korean experts believed the challenge for the younger Kim would come after his father's death.

Before Kim's passing, the U.S. administration had been expected this week to announce the resumption in food aid to North Korea and a potential bilateral meeting on nuclear disarmament. Although the State Department said there had been brief exchange with North Korean officials in New York on Monday, both initiatives are now in flux pending the end of the North's mourning period.

The administration says it is respecting that mourning period by understanding that North Korean officials will not be available for discussions. Yet it has steadfastly refused to express any sympathy for the death of Kim, whose Stalinist regime is accused of having one of the worst, if not the worst, human rights records in the world.

While showering the late Czech democracy leader Vaclev Havel with effusive eulogies, American officials have refused to even utter the word "condolence" in relation to Kim.

EDITOR'S NOTE ? Matthew Lee covers international affairs and U.S. foreign policy for The Associated Press.

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.msnbc.msn.com/id/45787168/ns/world_news-asia_pacific/

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Tuesday, December 27, 2011

Oil hovers below $100 amid low holiday volume (AP)

SINGAPORE ? Oil prices hovered below $100 a barrel Tuesday in Asia amid low holiday week trading volume.

Benchmark crude for February delivery was down 13 cents at $99.55 a barrel at late afternoon Singapore time in electronic trading on the New York Mercantile Exchange. The contract rose 15 cents to settle at $99.68 in New York on Friday.

In London, Brent crude was up 13 cents at $108.09 a barrel on the ICE Futures exchange.

Global oil trading markets were closed Monday for the Christmas holiday.

Crude briefly popped above $100 on Friday amid growing evidence the U.S. economy is improving. Some analysts say concerns that Europe's debt crisis will trigger a recession on the continent next year will overshadow any positive news out of the U.S. this week.

"We don't expect this strength to be maintained this week given a likely shift in focus back toward the eurozone where major debt issues remain largely unresolved," energy consultant Ritterbusch and Associates said in a report.

Because many traders are on vacation this week, trading volume is sharply lower and a few trades could jolt prices.

"Volume will be thin through this abbreviated week," energy consultant and trader The Schork Group said in a report. "As such, the potential exists for some wild swings."

In other Nymex trading, heating oil rose 0.8 cent to $2.91 per gallon and gasoline futures fell 0.5 cent at $2.67 per gallon. Natural gas futures were down 3.0 cents to $3.08 per 1,000 cubic feet.

Source: http://us.rd.yahoo.com/dailynews/rss/energy/*http%3A//news.yahoo.com/s/ap/20111227/ap_on_bi_ge/oil_prices

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Matthew McConaughey Engaged To Camila Alves

Couple have two children together and have been dating since 2006.
By Jocelyn Vena


Camila Alves and Matthew McConaughey
Photo: Joe Scarnici/Getty Images

Two kids and nearly six years later, Matthew McConaughey popped the question to his longtime lady love, model Camila Alves, over the holiday weekend. Her answer? A big yes! The actor confirmed the engagement on Twitter.

"Just asked camila to marry me, merry Christmas," he tweeted on Christmas Day, also posting a photo of him and Alves kissing next to Christmas decorations. The couple have a 3-year-old son, Levi, and a daughter, Vida, who turns 2 next month.

In the March issue of Esquire, the actor gushed about his bride-to-be. "Before this, I had a super home in the Hollywood Hills that I did by myself — landscaping, detailing pretty much everything. But that house was mine. And yeah, we coulda gone in there right away. Camila would have said, 'Fine, don't change a thing.' But I thought, 'I found the woman I wanna do it with, the woman I wanna make a family with, hopefully live our life out together.' She needs to have 50 percent of that," he said. "I mean, it's a lot easier for me to be at 100 percent. I'd always been 100 percent. It's braver for me at 50 percent."

In September 2008, McConaughey opened up to People about Alves, calling her "the love of my life." The two began dating in 2006. "I always wanted to be a father and thought it would be great, but it just took the right woman and the right time to make it all happen," he said. "We're a family now. I see the future and it's clearer to me now. Walking around with this cool responsibility all the time, it's a wonderful thing."

Share your well-wishes with the newly engaged couple in the comments below!

Source: http://www.mtv.com/news/articles/1676469/matthew-mcconaughey-engaged-camila-alves.jhtml

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Monday, December 26, 2011

Titleist Vokey SM4 Spin Milled Wedge Help Golf Celebrities Win the Game

Titleist has launched their newestTitleist Vokey SM4 Spin Milled Wedge, which aimed at renewing some of the spin lost following the change of groove regulations. The new Vokey wedge, called the SM4 because it is the 4th generation of Spin Milled wedge, features a new configuration with 17 grooves on the face with each one precisely milled right to the edge of the R&A's legal limit. I have never seen the wedge until I watch the game of Australia Open. So I decide to go to the online golf shop to buy one. After several rounds of hitting, I like it very much.

Titleist Vokey SM4 Spin Milled Wedge is so popular with players on International Tour since it has released by Bob. All Bob Vokey purpose of creating this golf clubs is study, create, and design wedges for players from the amateur 20 handicap to the elite touring pros. Tour players are usually pretty particular about their wedges as they are their scoring clubs and players such as Rory, Rickie, Scott Stallings and Brendan who have won the game by changing into the new SM4's right away. The touring pros play his wedges because they work the best.

The New Titleist Vokey SM4 Spin Milled Wedge has several advantages from models past. Bob spent a lot of time working on the SM4 wedges and through his new design, has been able to increase the spin over the SM3 by about 1000 to 1200rpms. He has also developed a new treatment for the grooves that help keep the grooves last longer and stay sharp. SM4 grooves allow for the Maximum conforming spin through tour proven extreme grooves that are totally inspected, maintain tight tolerance, and have the most aggressive groove edge at the limits allowed by the Rules of Golf.

The Titleist Vokey SM4 Spin Milled Wedge features grooves in order to allow for superior full shot control. Durability is always a key factor when selecting a wedge, and all SM4 Spin Milled wedges receive a localized heat treatment in the impact area that preserves the precise milled grooves and micro edges. Lastly, the SM4 Spin Milled wedges come in more loft, bounce and sole grinds than ever before. Go and get Vokey at online golf shop- you won't be regret to have this wedge in the golf greens.

Source: http://www.articlesbase.com/golf-articles/titleist-vokey-sm4-spin-milled-wedge-help-golf-celebrities-win-the-game-5517587.html

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Chinitech: RT @ralmn45 Gagnez sous le sapin la tablette tactile Apple iPad 2 WiFi blanc 16Go via @ilovetablette #SCTM4g - h... http://t.co/a04z6MuF

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Sunday, December 25, 2011

Control TV With Siri On iPhone With Tizi Remote (iOS App)

ADVERTISEMENTS

Remotes have been released for iPhones and iPod touches to control the television sets but this is something new and free. By the help of Tizi remote app and a dongle named Tizi go which costs ?139.99 and ?99.99 in the Germany as its not available out of Germany.

20111225-125904.jpg

The Tizi application is free in the App Store. After attaching the dongle to the iPad, place it where ever you want and control it by the Tizi application the shows, movies and music can be controlled by it plus with Siri too in the iPhone 4S.

via

Article by Absar Abdul Rehman

Absar has written 438 articles out of his expertize for us.

An another technology geek, who loves to teardown everything with his reviews, and speed of covering technology speed. Follow him on Google+

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GOP candidates to meet voters in SC, NH and Iowa

(AP) ? As the campaigns wind down for Christmas, three of the GOP presidential candidates will meet with voters in three different states on Friday.

Former Massachusetts Gov. Mitt Romney is wrapping up his three-day bus tour through New Hampshire, with appearances at the Tilt'n Diner in Tilton and in Concord at The Toy Factory before heading for lunch with the winner of "Grab a Bite with Mitt" contest at Dos Amigos Burritos.

Former House speaker Newt Gingrich heads to Columbia, S.C., for a town hall and a Christmas-season lunch at The Blue Marlin.

Minnesota Rep. Michele Bachmann continues her 99-county bus tour through Iowa, stopping in Bloomfield, Centerville, Corydon, Chariton, Pella and Newton.

Rick Perry, Jon Huntsman, Rick Santorum and Ron Paul have no campaign events scheduled until next week.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2011-12-23-GOP%20Campaign/id-c86b5ed641b0468caae96073647705de

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Saturday, December 24, 2011

Android Central staff #FollowFriday holiday edition

Follow the leaders

One of the few times throughout the year when there won't be a mountain of Android news is coming up.  We're talking about Christmas, of course, when the western world takes a few days off and we eat too much, drink too much, and spend time with our loved ones.  Everyone here at AC is stoked at the thought of all the Android phones and tablets that will be unwrapped come Christmas morning, and we;ll be sure to be watching our friends and followers on Google+ and Twitter to see how their holidays are going.  Join in the fun, and give us a shout to let us know how you're enjoying your holidays, or just to say hey.  Without you guys we wouldn't have near as much fun doing what we do here, and we appreciate each and every one of you.



Source: http://feedproxy.google.com/~r/androidcentral/~3/dRblSvjGsmE/story01.htm

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New Space Station Crew Set for Holiday Arrival Friday (SPACE.com)

Three spaceflyers who launched on a Russian rocket Wednesday (Dec. 21) are preparing to dock at the International Space Station tomorrow (Dec. 23), just in time for the holidays.

NASA astronaut Don Pettit, Russian cosmonaut Oleg Kononenko, and Dutch astronaut Andre Kuipers of the European Space Agency (ESA) are due to join the long-duration crew of the orbiting outpost for about five months.

The trio lifted off atop the Russian Soyuz TMA-03M spacecraft from the snowy Baikonur Cosmodrome in Kazakhstan at 8:16 a.m. EST (1316 GMT) on Wednesday. They are expected at the space station on Friday at 10:22 a.m. EST.

Waiting aboard the station are commander Daniel Burbank of NASA and Russian flight engineers Anton Shkaplerov and Anatoly Ivanishin. The new arrivals will return the space station's crew size back to its full six-person complement.

Deck the halls

The halls of the International Space Station are decked and Burbank, Shkaplerov and Ivanishin are looking forward to sharing a festive holiday season with their new crewmates once they arrive. [Holidays in Space: An Astronaut Photo Album]

"Our planet is so beautiful, peaceful and serene when you look at it from space ? the most beautiful holiday card you could imagine," Burbank wrote Dec. 17 on the astronaut blog Fragile Oasis. He and the other station residents have been setting up holiday decorationsand preparing for a big feast of space food after their crewmates arrive.

Though there will be Christmas cheer, the astronauts aren't expecting any gifts to arrive with the incoming Soyuz.

"In terms of gifts, when you're off in the frontier, you're not going to waste upmass on something like that," Pettit told SPACE.com in a preflight interview. "These holidays become matter of fact. My family gets to experience Christmas at Baikonur."

Packed schedule

The new crewmembers also won't have too much down time, as their schedule is packed with research and space station upkeep work.

They also plan to host the first visit of a commercial spacecraft to the orbiting laboratory. In February an unmanned SpaceX Dragon spacecraft will launch on the company's Falcon 9 rocket, carrying a haul of cargo to the space station. It will be the second orbital flight of Dragon, and the first to the outpost.

When it approaches the lab, the station crew will grab onto the capsule with the space station's robotic arm and berth it to the facility.

"We're prepared to do whatever happens during our mission in terms of a visiting vehicle profile," Pettit said. "It looks like we are going to be longshoremen."

International cooperation

Now that NASA's space shuttles are retired, the agency is hoping commercial spacecraft can fill in the gap, first to carry cargo, and eventually people, to the space station, which is set to operate until at least 2020.

In the meantime, U.S. astronauts will continue riding on Russian Soyuz spacecraft until a private American alternative is available. Russian, European and Japanese automated vehicles will deliver cargo.

The $100 billion, football field-size space station is a partnership between the United States, Russia, Europe, Japan and Canada.

"I think space has been a sports arena," Kononenko said during a preflight press conference."I think the future of space exploration belongs only to joint exploration, and we will be able to do deep space missions only if we cooperate together."

You can follow SPACE.com assistant managing editor Clara Moskowitz on Twitter @ClaraMoskowitz. Follow SPACE.com for the latest in space science and exploration news on Twitter @Spacedotcom and on Facebook.

Source: http://us.rd.yahoo.com/dailynews/rss/science/*http%3A//news.yahoo.com/s/space/20111222/sc_space/newspacestationcrewsetforholidayarrivalfriday

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Friday, December 23, 2011

US targeted over failure to condemn Israel (AP)

UNITED NATIONS ? Fourteen frustrated members of the U.N. Security Council pointed a finger at the United States Tuesday for blocking any condemnation of Israel's accelerated settlement construction in Palestinian territory.

In a move which Russia's U.N. Ambassador Vitaly Churkin called historic, diplomats from almost all regional blocs represented on the council stepped to the microphone Tuesday after closed council consultations on the Mideast to condemn the lack of progress toward a solution of the Israeli-Palestinian conflict.

Churkin, the current council president, said the frustration over the impasse in Israeli-Palestinian talks spilled out in statements from the four European Union council members, the Nonaligned Movement, the Arab group, and the group of emerging powers that includes India, Brazil and South Africa.

Clearly referring to the United States, Churkin said dismissively that one delegation believes things will "miraculously" sort themselves out on their own.

"The call for bilateral negotiations without preconditions would seem a normal thing to ask for," he said.

But Churkin said the Palestinians are overwhelmed militarily and in every other way by the Israelis and without preconditions they would not get a fair shake in negotiations.

The diplomats ? including key U.S. allies in Europe ? also criticized the council's failure to take action against escalating violence by Israeli settlers and urged a speedy resumption of Israeli-Palestinian negotiations.

Britain's U.N. Ambassador Mark Lyall Grant, also speaking for EU members France, Germany and Portugal, said "Israel's security and the realization of the Palestinians' right to statehood are not opposing goals."

"On the contrary they are mutually reinforcing objectives," he said. "But they will not be achieved while settlement building and settler violence continues."

South Africa's U.N. Ambassador Baso Sangqu, speaking on behalf of the Nonaligned Movement of mainly developing countries, said settler attacks against Palestinian civilians increased 50 percent this year and called Israeli settlement construction "the main impediment for the two-state solution of the Israeli-Palestinian conflict."

While the United States was not mentioned by name, the diplomats anger was clearly directed at Washington which vetoed a resolution in February backed by the 14 other council members that would have demanded an immediate halt to all settlement building. The Obama administration has also promised to veto any Security Council resolution supporting Palestine's bid to become the 194th member of the United Nations.

The U.S. has said repeatedly it does not support settlement building. But Payton Knopf, the U.S. Mission's deputy spokesman, told AP "the only way to resolve the outstanding issues between Israelis and Palestinians is through serious and substantive direct negotiations."

The United States also opposes Security Council action on "final status issues" because this "would only harden the positions of both sides and make the resumption of negotiations more difficult," Knopf said.

The Palestinians insist they will not resume peace talks until Israel halts settlement building in the West Bank and East Jerusalem, which they want as a capital. Israeli-Palestinian peace talks collapsed just weeks after they restarted in September 2010 because Israel ended a 10-month moratorium on settlement construction.

Karean Peretz, spokeswoman for Israel's U.N. Mission, questioned why the Security Council was focusing on settlements but remained "silent and paralyzed" on pressing issues including civilian killings in Syria, terrorist groups operating in Gaza, attacks on U.N. forces in Lebanon and Iran's quest for nuclear weapons.

"The main obstacle to peace, has been, and remains, the Palestinians' claim to the so-called right of return (for refugees) and its refusal to recognize Israel as a Jewish state," she told AP.

Source: http://us.rd.yahoo.com/dailynews/rss/mideast/*http%3A//news.yahoo.com/s/ap/20111220/ap_on_re_us/un_un_palestinians_israel

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Thursday, December 22, 2011

China village ends protests after government compromise (Reuters)

WUKAN, China (Reuters) ? A Chinese village protest that tested the ruling Communist Party for over a week ended on Wednesday after officials offered concessions over seized farmland and the death of a village leader, in a rare spectacle of the government backing down to mobilized citizens.

Residents of Wukan, in southern Guangdong province, had fended off police with barricades and held protests over the death in police custody of activist Xue Jinbo, whose family rejects the government's position that he died of natural causes, and against the seizure of farmland for development.

But after talks with officials, village representatives told residents to pull down protest banners and go back to their normal lives -- provided the government keeps to its word.

"Because this matter has been achieved, we won't persist in making noise," village organizer, Yang Semao, told an assembly hall of village representatives and reporters, referring to the protests. He said protest banners would be taken down.

"They've agreed to our initial requests," Yang told Reuters. But he added a caveat: "If the government doesn't meet its commitments, we'll protest again."

Senior officials negotiating with villagers agreed to release three men held over land protests in September, when a government office was trashed, and to re-examine the cause of Xue's death, a village organizer said earlier.

Xue's family and fellow villagers believe he was subjected to abuse that left injuries on his body. But the government said an autopsy showed he died of heart problems. Xue was detained over the land protests that broke out in September.

The concessions showed how eager higher leaders were to avoid the risk of fresh violence and bloodshed, said Ting Wai, political science professor at Hong Kong Baptist University.

"I think the local government did not want to make concessions, and then of course when time goes on, the people became more and more frustrated, and now it is really like a bomb, so in order to prevent the bomb from exploding the provincial government has to do something," he said.

Underscoring government fears of unrest, in a separate protest on Tuesday in Haimen, a town further east up the coast from Wukan, residents demonstrated in front of government offices and blocked a highway over plans to build a power plant.

State media said on Wednesday the government had agreed to suspend construction, though there was another protest which partially blocked a highway.

Chinese officials sometimes make low-key concessions to local protests, especially after they are over, and also punish protest organizers. But Wukan turned negotiations into a rare public spectacle, watched by foreign reporters and discussed within China -- despite domestic censorship of news.

Under a hot afternoon sun, a thousand villagers gathered to hear an organizer, Lin Zuluan, explain the concessions from the government, which they greeted with loud clapping.

He later told reporters that villagers would not suffer retribution for taking part in the protests.

WARY OF GOVERNMENT PROMISES

Some Wukan residents were wary of the government's promises.

"Our hearts are not at ease," said Zhong Xianmei, a resident in her thirties. "The dead body isn't back, are the detained back in their homes? Will their words count?"

Wang Yang, the Communist Party chief of Guangdong, obliquely acknowledged that the villagers had cause to complain, in comments published on Wednesday in the Southern Daily, the official province newspaper.

"This is the outcome of conflicts that accumulated over a long time in the course of economic and social development," said Wang, seen by many analysts as nursing hopes of a spot in China's next central leadership.

Guangdong is a prosperous part of China. But the upheavals of urbanization and industrialization have fanned discontent among increasingly assertive citizens, who often blame local officials for corruption and abuses.

Rural land in China is usually owned in name by village collectives. But in fact, government officials can mandate seizing land for development in return for compensation, which villagers often say is inadequate.

Protests in China have become relatively common over corruption, pollution, wages, and land grabs that local officials justify in the name of development.

Chinese experts put the number of "mass incidents," as such protests are known, at about 90,000 a year in recent years.

China's leaders, determined to maintain one-party control, worry that such outbursts might turn into broader and more persistent challenges to their power.

But even in Wukan, villagers professed faith in the central government. On Wednesday morning, about 300 of them lined the sides of a road into the village, preparing to welcome Zhu Mingguo, the main official negotiating with them.

Zhu promised an impartial autopsy for the late Xue, and "transparent" disclosure in the media of how the villagers' grievances are addressed, according to a report in the province's official newspaper, the Southern Daily.

Lin Zuluan, the Wukan organizer, told reporters that officials also agreed that the village can hold democratic elections. In China, village committees are in theory elected, but in practice there are many restrictions -- formal and informal -- on votes.

(Writing by Chris Buckley; Additional reporting by Sisi Tang in Hong Kong and Chris Buckley in Beijing; Editing by Ken Wills, Robert Birsel, Alex Richardson and Ron Popeski)

Source: http://us.rd.yahoo.com/dailynews/rss/china/*http%3A//news.yahoo.com/s/nm/20111221/wl_nm/us_china_unrest

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Monday, December 19, 2011

Mars and the Moon Dance in Tonight's Night Sky (SPACE.com)

If you're out during the very late evening hours tonight (Dec. 16), check out the eastern sky just before midnight.?

There you'll see a waning gibbous moon less than a day before it arrives at last quarter (half) phase. Hovering well off to its left and at a slightly higher altitude above the horizon is a rather conspicuous "star," shining with a fiery tint, which is the planet Mars.?

The apparent distance between the moon and Mars is relatively wide, measuring approximately 8 degrees (your clenched fist held at arm's length measures about 10 degrees). Although they are not particularly close, Mars calls attention to itself, in part, due to its color as well as its brightness. The sky map of Mars and the moon here shows how they appear together in the night sky.

The moon, of course, is much closer to Earth than Mars and appears to cycle around the sky against the background stars rather quickly over a span of about 29.5-days. It will, in fact, be passing Mars again in about a month, on the evening of Jan. 13. [Photos: Our Changing Moon]

But between now and then Mars is going to become far more prominent in our sky.

Between tonight and its next encounter with the moon in mid-January, Mars will appear to travel part of the distance from the star Regulus in the constellation Leo to Spica in Virgo; it will pass from Leo into Virgo in mid-January.

Currently, Mars rises around 11 p.m. local time. But by Jan. 13, it will be coming up before 9:45 p.m.

The planet is highest in the south at dawn's first light: an orange-yellow gem that's brightening weekly. From now until its next rendezvous with the moon in mid-January, Mars will flame up, nearly doubling in brightness from its current magnitude of +0.5 (which rivals the ruddy star Betelgeuse in Orion) to a dazzling -0.1 (equaling the similarly hued star Arcturus in Bootes).?

This brightening results from the planet's rapidly decreasing distance from Earth, from 1.174 to 0.926 times the span from the Earth to the sun (109 million to 86 million miles). Each day, Mars moves, on average, about 852,000 miles closer to us.?

The Martian polar cap should be fully emerged from its winter cloud cover by mid-January, and likely will be a prominent bright spot on the disk's northern limb.

Although Mars is moving Earthward in December, you'll still need a steady atmosphere at dawn and at least a medium-size telescope to glimpse any surface features on the little ocher globe.

But don't be pessimistic. The Martian disk will grow 21 percent larger during the next four weeks and the polar cap should be fully emerged from its winter cloud cover by mid-January, likely providing a prominent bright spot on the disk's northern limb. Bottom line: It will soon be time to start turning telescopes toward the Red Planet!

Mars will arrive at opposition to the sun on March 3 and will be closest to Earth two days later. In the meantime, enjoy its rather wide encounter with the moon late tonight.

Joe Rao serves as an instructor and guest lecturer at New York's Hayden Planetarium. He writes about astronomy for The New York Times and other publications, and he is also an on-camera meteorologist for News 12 Westchester, New York.

Source: http://us.rd.yahoo.com/dailynews/rss/space/*http%3A//news.yahoo.com/s/space/20111216/sc_space/marsandthemoondanceintonightsnightsky

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Sunday, December 18, 2011

Britney Spears engaged to marry Jason Trawick

FILE - In this May 11, 2011 file photo, singer Britney Spears, right, and Jason Trawick arrive at an Evening of "Southern Style" in Beverly Hills, Calif. Trawick announced Friday, dec. 16, 2011, on ?Access Hollywood? that he and Spears are engaged. The two have been dating since 2009. (AP Photo/Matt Sayles, file)

FILE - In this May 11, 2011 file photo, singer Britney Spears, right, and Jason Trawick arrive at an Evening of "Southern Style" in Beverly Hills, Calif. Trawick announced Friday, dec. 16, 2011, on ?Access Hollywood? that he and Spears are engaged. The two have been dating since 2009. (AP Photo/Matt Sayles, file)

(AP) ? Britney Spears is ready to walk down the aisle for the third time. The 30-year-old pop star has agreed to marry her longtime boyfriend and former agent Jason Trawick.

Trawick announced Friday on "Access Hollywood" that he and Spears are engaged. The two have been dating since 2009.

Spears hinted at the big news with a tweet Friday morning that read, "OMG. Last night Jason surprised me with the one gift I've been waiting for. Can't wait to show you! SO SO SO excited!!!!"

Spears was previously married to Kevin Federline, with whom she has two sons: 6-year-old Sean Preston and 5-year-old Jayden James. The couple divorced in 2006. Spears also briefly wed childhood friend Jason Alexander in 2004, but the marriage was annulled after 55 hours.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2011-12-16-People-Britney%20Spears/id-96e377708c214591ae797bfaa1729955

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Saturday, December 17, 2011

Metabolomx test detects lung cancer from breath

Metabolomx test detects lung cancer from breath [ Back to EurekAlert! ] Public release date: 15-Dec-2011
[ | E-mail | Share Share ]

Contact: Justin Jackson
jjackson@burnsmc.com
212-213-0006
Burns McClellan

Test also differentiates between types and stages of lung cancer; study results for Metabolomx' colorimetric sensor array published in the Journal of Thoracic Oncology

Mountain View, CA December 15, 2011 Metabolomx, a diagnostic company focused on the detection of the metabolomics signature of cancer from exhaled breath, today announces publication of results from the first clinical study demonstrating a breath test that can both detect lung cancer and differentiate between types of lung cancer in humans. This seminal study, conducted at the Cleveland Clinic and led by Dr. Peter Mazzone, used Metabolomx' first-generation colorimetric sensor array, and reported accuracy exceeding 80% in lung cancer detection, comparable to computerized tomography (CT) scan. Further, the study found that Metabolomx' first-generation colorimetric sensor array could identify the subtype of lung cancer (small cell versus adenocarcinoma versus squamous cell) with accuracy approaching 90%.

The availability of a low-cost, non-invasive metabolomic breath signature for lung cancer is particularly timely given the recently announced results of the National Cancer Institute's National Lung Screening Trial (NLST) calling for wider CT screening of high-risk citizens. The breath signature, which reports active tumor metabolism, is thought to provide complementary information to CT, potentially helping clinicians distinguish benign from malignant lung nodules.

The sensor detects the unique pattern of volatile organic compounds (the "metabolic biosignature") present in exhaled breath. The article, "Exhaled Breath Analysis with a Colorimetric Sensor Array for the Identification and Characterization of Lung Cancer," is appearing in the current, online issue of the Journal of Thoracic Oncology (JTO), the official Journal of the International Association for the Study of Lung Cancer.

James R. Jett, MD, Pulmonary Medicine and Medical Oncology, National Jewish Health and Editor-in-Chief of the Journal of Thoracic Oncology, stated, "The JTO is dedicated to publishing the best in clinical research that may one day make a real difference in the care of patients. The currently reported results, should they be confirmed in additional clinical testing, provide a provocative challenge for us to look more closely at 'biosignatures,' as described in the journal article, that may be complementary to detection modalities such as CT scan. The advent of the NLST results demonstrating the value of CT heightens the need for non-invasive, low-cost companion diagnostics, and a metabolomic breath test, if born out in continuing studies, is a candidate to play that role in early lung cancer detection."

"The Cleveland Clinic results just published by the Journal of Thoracic Oncology, the reference journal for lung cancer, demonstrate the broad potential for use of breath analysis in the early detection of lung cancer," commented Paul Rhodes, PhD, Founder and CEO of Metabolomx. "These results show that the first generation of our breath test technology compares well with CT scans. Detection of the metabolomic signature of lung cancer in exhaled breath is non-invasive, rapid, and inexpensive, and will become a valuable adjunct to help assess an indeterminate CT, and may come to have a central role in early detection and differentiation of lung cancer, while lowering costs to the healthcare system."

The article was authored by Peter J. Mazzone, MD, MPH, Cleveland Clinic; Xiao-Feng Wang, PhD, Cleveland Clinic; Yaomin Xu, PhD, Cleveland Clinic; Tarek Mekhail, MD, MSc, Florida Hospital; Mary C. Beukemann, Cleveland Clinic; Jie Na, MS, Cleveland Clinic; Jonathan W. Kemling, PhD, University of Illinois, Chicago; Kenneth S. Suslick, PhD, University of Illinois, Chicago; and Madhu Sasidhar, MD, Cleveland Clinic. Initial results from this study were presented at the American College of Chest Physicians conference in November 2010.

Dr. Mazzone commented, "Our research shows that breath testing may help identify patients with lung cancer, as well as provide us with information that can help with treatment decisions, such as the type of lung cancer, its stage, and prognosis. The accuracy of these non-invasive tests can be further augmented when combined with existing clinical predictors, such as health status and age."

Metabolomx has begun trials of its next-generation sensor array system in an ongoing lung cancer study at the Cleveland Clinic. The Company expects their current generation system to be over 100 times more sensitive at detecting breath chemicals, which are often present in very low concentrations, than the system used in the published study.

About the Study

The study, conducted at the Cleveland Clinic and led by Dr. Peter Mazzone, was designed to develop an exhaled breath biosignature of lung cancer using Metabolomx' colorimetric sensor array and to determine the accuracy of breath biosignatures of lung cancer characteristics with and without the inclusion of clinical risk factors. Breath samples were drawn from 229 individuals, 92 with biopsy-proven, untreated lung cancer and 137 either at a risk for developing lung cancer or with indeterminate lung nodules. Logistic prediction models were developed and statistically validated based on the color changes of the sensor. Age, sex, smoking history, and chronic obstructive pulmonary disease were incorporated in the prediction models.

Key Study Results

  • Approximately 81% accuracy for the detection of lung cancer without regard for subtype
  • Approximately 83%, 85%, and 89% accuracy in discriminating patients with adenocarcinoma, squamous cell, and small cell lung cancer versus controls, demonstrating that the breath test can differentiate lung cancer subtype - the first diagnostic announced to do so.
  • An ability to differentiate Stage I/II from Stage III/IV (approximately 79% accuracy) indicating the ability to identify lung cancer at the earliest stages.

###

About Metabolomx

Metabolomx has developed and owns all worldwide rights to the foremost breath test for cancer. By engaging some of the brightest minds in the fields of artificial and biological olfactory sensor arrays, neural processing and product development, Metabolomx has developed and tested an artificial olfactory sensor technology that recognizes the molecular fingerprint of the disease signature in breath. Metabolomx' technology is enabling the non-invasive, rapid, inexpensive and early diagnosis of lung cancer and other cancers. Metabolomx is located in Mountain View, CA. For additional information on the Company, please visit www.metabolomx.com.

Contacts

Media on behalf of Metabolomx
Justin Jackson
Michelle Szwarcberg
Burns McClellan
Tel: +1-212-213-0006
Email: jjackson@burnsmc.com
mszwarcberg@burnsmc.com


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Metabolomx test detects lung cancer from breath [ Back to EurekAlert! ] Public release date: 15-Dec-2011
[ | E-mail | Share Share ]

Contact: Justin Jackson
jjackson@burnsmc.com
212-213-0006
Burns McClellan

Test also differentiates between types and stages of lung cancer; study results for Metabolomx' colorimetric sensor array published in the Journal of Thoracic Oncology

Mountain View, CA December 15, 2011 Metabolomx, a diagnostic company focused on the detection of the metabolomics signature of cancer from exhaled breath, today announces publication of results from the first clinical study demonstrating a breath test that can both detect lung cancer and differentiate between types of lung cancer in humans. This seminal study, conducted at the Cleveland Clinic and led by Dr. Peter Mazzone, used Metabolomx' first-generation colorimetric sensor array, and reported accuracy exceeding 80% in lung cancer detection, comparable to computerized tomography (CT) scan. Further, the study found that Metabolomx' first-generation colorimetric sensor array could identify the subtype of lung cancer (small cell versus adenocarcinoma versus squamous cell) with accuracy approaching 90%.

The availability of a low-cost, non-invasive metabolomic breath signature for lung cancer is particularly timely given the recently announced results of the National Cancer Institute's National Lung Screening Trial (NLST) calling for wider CT screening of high-risk citizens. The breath signature, which reports active tumor metabolism, is thought to provide complementary information to CT, potentially helping clinicians distinguish benign from malignant lung nodules.

The sensor detects the unique pattern of volatile organic compounds (the "metabolic biosignature") present in exhaled breath. The article, "Exhaled Breath Analysis with a Colorimetric Sensor Array for the Identification and Characterization of Lung Cancer," is appearing in the current, online issue of the Journal of Thoracic Oncology (JTO), the official Journal of the International Association for the Study of Lung Cancer.

James R. Jett, MD, Pulmonary Medicine and Medical Oncology, National Jewish Health and Editor-in-Chief of the Journal of Thoracic Oncology, stated, "The JTO is dedicated to publishing the best in clinical research that may one day make a real difference in the care of patients. The currently reported results, should they be confirmed in additional clinical testing, provide a provocative challenge for us to look more closely at 'biosignatures,' as described in the journal article, that may be complementary to detection modalities such as CT scan. The advent of the NLST results demonstrating the value of CT heightens the need for non-invasive, low-cost companion diagnostics, and a metabolomic breath test, if born out in continuing studies, is a candidate to play that role in early lung cancer detection."

"The Cleveland Clinic results just published by the Journal of Thoracic Oncology, the reference journal for lung cancer, demonstrate the broad potential for use of breath analysis in the early detection of lung cancer," commented Paul Rhodes, PhD, Founder and CEO of Metabolomx. "These results show that the first generation of our breath test technology compares well with CT scans. Detection of the metabolomic signature of lung cancer in exhaled breath is non-invasive, rapid, and inexpensive, and will become a valuable adjunct to help assess an indeterminate CT, and may come to have a central role in early detection and differentiation of lung cancer, while lowering costs to the healthcare system."

The article was authored by Peter J. Mazzone, MD, MPH, Cleveland Clinic; Xiao-Feng Wang, PhD, Cleveland Clinic; Yaomin Xu, PhD, Cleveland Clinic; Tarek Mekhail, MD, MSc, Florida Hospital; Mary C. Beukemann, Cleveland Clinic; Jie Na, MS, Cleveland Clinic; Jonathan W. Kemling, PhD, University of Illinois, Chicago; Kenneth S. Suslick, PhD, University of Illinois, Chicago; and Madhu Sasidhar, MD, Cleveland Clinic. Initial results from this study were presented at the American College of Chest Physicians conference in November 2010.

Dr. Mazzone commented, "Our research shows that breath testing may help identify patients with lung cancer, as well as provide us with information that can help with treatment decisions, such as the type of lung cancer, its stage, and prognosis. The accuracy of these non-invasive tests can be further augmented when combined with existing clinical predictors, such as health status and age."

Metabolomx has begun trials of its next-generation sensor array system in an ongoing lung cancer study at the Cleveland Clinic. The Company expects their current generation system to be over 100 times more sensitive at detecting breath chemicals, which are often present in very low concentrations, than the system used in the published study.

About the Study

The study, conducted at the Cleveland Clinic and led by Dr. Peter Mazzone, was designed to develop an exhaled breath biosignature of lung cancer using Metabolomx' colorimetric sensor array and to determine the accuracy of breath biosignatures of lung cancer characteristics with and without the inclusion of clinical risk factors. Breath samples were drawn from 229 individuals, 92 with biopsy-proven, untreated lung cancer and 137 either at a risk for developing lung cancer or with indeterminate lung nodules. Logistic prediction models were developed and statistically validated based on the color changes of the sensor. Age, sex, smoking history, and chronic obstructive pulmonary disease were incorporated in the prediction models.

Key Study Results

  • Approximately 81% accuracy for the detection of lung cancer without regard for subtype
  • Approximately 83%, 85%, and 89% accuracy in discriminating patients with adenocarcinoma, squamous cell, and small cell lung cancer versus controls, demonstrating that the breath test can differentiate lung cancer subtype - the first diagnostic announced to do so.
  • An ability to differentiate Stage I/II from Stage III/IV (approximately 79% accuracy) indicating the ability to identify lung cancer at the earliest stages.

###

About Metabolomx

Metabolomx has developed and owns all worldwide rights to the foremost breath test for cancer. By engaging some of the brightest minds in the fields of artificial and biological olfactory sensor arrays, neural processing and product development, Metabolomx has developed and tested an artificial olfactory sensor technology that recognizes the molecular fingerprint of the disease signature in breath. Metabolomx' technology is enabling the non-invasive, rapid, inexpensive and early diagnosis of lung cancer and other cancers. Metabolomx is located in Mountain View, CA. For additional information on the Company, please visit www.metabolomx.com.

Contacts

Media on behalf of Metabolomx
Justin Jackson
Michelle Szwarcberg
Burns McClellan
Tel: +1-212-213-0006
Email: jjackson@burnsmc.com
mszwarcberg@burnsmc.com


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-12/bm-mtd121411.php

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